Alzheimer’s Could Be A White Matter Disease, Not Gray Authored by RJ Tesi via RealClearScience, Alzheimer’s disease (Alzheimer’s) is conceptualized as a progressive consequence of two hallmark pathological changes in gray matter, in particular, extracellular amyloid plaques and neurofibrillary tangles. However, over the past several years, neuroimaging studies have implicated micro and microstructural abnormalities in white matter in the risk and progression of Alzheimer’s, suggesting that in addition to the neuronal pathology characteristic of the disease, white matter degeneration and demyelination are crucial features of patients living with the disease. A shift to focus on white matter abnormalities, rather than… — Continue at ZeroHedge News : Read More